Sequence Detail

ID/Version

P70312 P70411 Q62405 Q68EF7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Hyaluronan synthase 2; EC=2.4.1.212 {ECO:0000269|PubMed:10455188};AltName: Full=Hyaluronate synthase 2;AltName: Full=Hyaluronic acid synthase 2; Short=HA synthase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 552 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Has2	hyaluronan synthase 2	55	118	3	19

Sequence references in MGI

J:33034 Semino CE, et al., Homologs of the Xenopus developmental gene DG42 are present in zebrafish and mouse and are involved in the synthesis of Nod-like chitin oligosaccharides during early embryogenesis. Proc Natl Acad Sci U S A. 1996 May 14;93(10):4548-53
J:35498 Spicer AP, et al., Molecular cloning and characterization of a putative mouse hyaluronan synthase. J Biol Chem. 1996 Sep 20;271(38):23400-6
J:37703 Fulop C, et al., Coding sequence of a hyaluronan synthase homologue expressed during expansion of the mouse cumulus-oocyte complex. Arch Biochem Biophys. 1997 Jan 15;337(2):261-6
J:63748 Camenisch TD, et al., Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme [see comments]. J Clin Invest. 2000 Aug;106(3):349-60
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:200337 Itano N, et al., Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J Biol Chem. 1999 Aug 27;274(35):25085-92