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Sequence Detail
ID/Version
P70227 Q8CED5 Q91Z08 Q5DWM4 (UniProt | EBI) Last sequence update: 2005-10-25
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 {ECO:0000305};AltName: Full=IP3 receptor isoform 3; Short=IP3R-3 {ECO:0000250|UniProtKB:Q63269}; Short=InsP3R3;AltName: Full=Inositol 1,4,5-trisphosphate receptor type
Provider SWISS-PROT
Sequence
Polypeptide 2670 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Itpr3 inositol 1,4,5-triphosphate receptor 3 71 102 3 41
Sequence references in MGI J:2208 Ross CA, et al., Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4265-9
J:59593 De Smedt H, et al., Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin. Biochem J. 1997 Mar 1;322(Pt 2):575-83
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166717 Giorgi C, et al., PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science. 2010 Nov 26;330(6008):1247-51
J:170219 Yamazaki H, et al., Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening. J Biol Chem. 2010 Nov 12;285(46):36081-91
J:203403 Shindo Y, et al., Lrmp/Jaw1 is expressed in sweet, bitter, and umami receptor-expressing cells. Chem Senses. 2010 Feb;35(2):171-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory