Sequence Detail

ID/Version

P70211 G3X9X6 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Netrin receptor DCC;AltName: Full=Tumor suppressor protein DCC;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1447 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dcc	DCC netrin 1 receptor	34	161	3	12

Sequence references in MGI

J:30261 Cooper HM, et al., Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo. Oncogene. 1995 Dec 7;11(11):2243-54
J:143806 Ly A, et al., DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell. 2008 Jun 27;133(7):1241-54
J:184952 Wei P, et al., The Cbln family of proteins interact with multiple signaling pathways. J Neurochem. 2012 Jun;121(5):717-29
J:261685 Jamuar SS, et al., Biallelic mutations in human DCC cause developmental split-brain syndrome. Nat Genet. 2017 Apr;49(4):606-612
J:269669 Rong Y, et al., Glycosylation of Cblns attenuates their receptor binding. Brain Res. 2018 Sep 1;1694:129-139
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89