Sequence Detail

ID/Version

P69744 Q2TB50 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transient receptor potential cation channel subfamily V member 5; Short=TrpV5;AltName: Full=Calcium transport protein 2; Short=CaT2;AltName: Full=Epithelial calcium channel 1; Short=ECaC1;AltName: Full=Osm-9-like TRP

Provider

SWISS-PROT

Sequence

Polypeptide 723 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trpv5	transient receptor potential cation channel, subfamily V, member 5	57	106	3	6

Sequence references in MGI

J:78617 Nilius B, et al., Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3. J Biol Chem. 2002 Aug 23;277(34):30852-8
J:86949 Hoenderop JG, et al., Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5. J Clin Invest. 2003 Dec;112(12):1906-14
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113972 Hoenderop JG, et al., Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6. EMBO J. 2003 Feb 17;22(4):776-85
J:248011 van der Eerden BC, et al., Lifelong challenge of calcium homeostasis in male mice lacking TRPV5 leads to changes in bone and calcium metabolism. Oncotarget. 2016 May 03;7(18):24928-41
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89