Sequence Detail

ID/Version

P68368 Q3TY31 P05215 (UniProt | EBI)

Last sequence update: 1987-08-13
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Tubulin alpha-4A chain; EC=3.6.5.- {ECO:0000250|UniProtKB:P68363};AltName: Full=Alpha-tubulin 4;AltName: Full=Alpha-tubulin isotype M-alpha-4;AltName: Full=Tubulin alpha-4 chain;

Provider

SWISS-PROT

Sequence

Polypeptide 448 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tuba4a	tubulin, alpha 4A	14	101	3	15

Sequence references in MGI

J:25928 Villasante A, et al., Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes. Mol Cell Biol. 1986 Jul;6(7):2409-19
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:150280 Rogowski K, et al., Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. Cell. 2009 Jun 12;137(6):1076-87
J:201638 Bosch Grau M, et al., Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia. J Cell Biol. 2013 Aug 5;202(3):441-51
J:237484 Weidemann M, et al., CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility. Development. 2016 Dec 15;143(24):4736-4748
J:241131 Janke C, et al., Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science. 2005 Jun 17;308(5729):1758-62
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:300009 Gadadhar S, et al., Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility. Science. 2021 Jan 8;371(6525)