Sequence Detail

ID/Version

P63250 P35562 (UniProt | EBI)

Last sequence update: 2004-10-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=G protein-activated inward rectifier potassium channel 1; Short=GIRK-1;AltName: Full=Inward rectifier K(+) channel Kir3.1;AltName: Full=Potassium channel, inwardly rectifying subfamily J member 3;

Provider

SWISS-PROT

Sequence

Polypeptide 501 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	42	102	4	10

Sequence references in MGI

J:24178 Kobayashi T, et al., Molecular cloning of a mouse G-protein-activated K+ channel (mGIRK1) and distinct distributions of three GIRK (GIRK1, 2 and 3) mRNAs in mouse brain. Biochem Biophys Res Commun. 1995 Mar 28;208(3):1166-73
J:80991 Nishida M, et al., Structural Basis of Inward Rectification. Cytoplasmic Pore of the G Protein-Gated Inward Rectifier GIRK1 at 1.8 A Resolution. Cell. 2002 Dec 27;111(7):957-65
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:359363 Jelacic TM, et al., Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3. J Membr Biol. 1999 May 15;169(2):123-9
J:360508 Lippiello P, et al., GIRK1-Mediated Inwardly Rectifying Potassium Current Is a Candidate Mechanism Behind Purkinje Cell Excitability, Plasticity, and Neuromodulation. Cerebellum. 2020 Dec;19(6):751-761