Sequence Detail

ID/Version

P63015 P70601 Q8VDB5 P32117 Q62222 Q921Q8 Q3UTV5 Q8CEI5 Q64037 (UniProt | EBI)

Last sequence update: 2004-08-31
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Paired box protein Pax-6;AltName: Full=Oculorhombin;

Provider

SWISS-PROT

Sequence

Polypeptide 422 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pax6	paired box 6	239	669	4	76

Sequence references in MGI

J:886 Ton CC, et al., Small eye (Sey): cloning and characterization of the murine homolog of the human aniridia gene. Genomics. 1992 Jun;13(2):251-6
J:1914 Walther C, et al., Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 1991 Dec;113(4):1435-49
J:2301 Hill RE, et al., Mouse small eye results from mutations in a paired-like homeobox-containing gene [published erratum appears in Nature 1992 Feb 20;355(6362):750]. Nature. 1991 Dec 19-26;354(6354):522-5
J:11577 Walther C, et al., Pax: a murine multigene family of paired box-containing genes. Genomics. 1991 Oct;11(2):424-34
J:40439 St-Onge L, et al., Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. Nature. 1997 May 22;387(6631):406-9
J:73625 Favor J, et al., Molecular Characterization of Pax6(2Neu) Through Pax6(10Neu). An extension of the pax6 allelic series and the identification of two possible hypomorph alleles in the mouse mus musculus. Genetics. 2001 Dec;159(4):1689-700
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137611 Tuoc TC, et al., Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system. Genes Dev. 2008 Jul 15;22(14):1972-86
J:167158 Yan Q, et al., Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21034-9
J:297319 Kogawa M, et al., The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. J Biol Chem. 2013 Oct 25;288(43):31299-312