Sequence Detail

ID/Version

P63013 Q02810 P43271 Q569N6 (UniProt | EBI)

Last sequence update: 2004-08-31
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Paired mesoderm homeobox protein 1;AltName: Full=Homeobox protein K-2;AltName: Full=Muscle homeobox protein {ECO:0000303|PubMed:1360403}; Short=MHox {ECO:0000303|PubMed:1360403};AltName: Full=Paired-related homeobox protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 245 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prrx1	paired related homeobox 1	55	159	4	16

Sequence references in MGI

J:3255 Kern MJ, et al., A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy. Nucleic Acids Res. 1992 Oct 11;20(19):5189-95
J:16732 Kern MJ, et al., Genomic organization and chromosome localization of the murine homeobox gene Pmx. Genomics. 1994 Jan 15;19(2):334-40
J:25923 Cserjesi P, et al., MHox: a mesodermally restricted homeodomain protein that binds an essential site in the muscle creatine kinase enhancer. Development. 1992 Aug;115(4):1087-101
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:342646 Liu H, et al., Prrx1 marks stem cells for bone, white adipose tissue and dermis in adult mice. Nat Genet. 2022 Dec;54(12):1946-1958
J:349681 Lee KW, et al., PRRX1 is a master transcription factor of stromal fibroblasts for myofibroblastic lineage progression. Nat Commun. 2022 May 19;13(1):2793