Sequence Detail

ID/Version

P63002 Q06195 (UniProt | EBI)

Last sequence update: 2004-08-31
Last annotation update: 2026-01-28

Sequence description from provider

RecName: Full=TLE family member 5 {ECO:0000305};AltName: Full=Amino-terminal enhancer of split; Short=Amino enhancer of split;AltName: Full=Grg-5;AltName: Full=Groucho-related protein 5;AltName: Full=Protein ESP1;AltName: Full=Protein GRG;

Provider

SWISS-PROT

Sequence

Polypeptide 197 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tle5	TLE family member 5, transcriptional modulator	36	116	4	19

Sequence references in MGI

J:13403 Mallo M, et al., Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex. Mech Dev. 1993 Jul;42(1-2):67-76
J:14582 Miyasaka H, et al., Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein. Eur J Biochem. 1993 Aug 15;216(1):343-52
J:77680 Zhu CC, et al., Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors. Development. 2002 Jun;129(12):2835-49
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89