Sequence Detail

ID/Version

P62960 P22568 P27817 P43482 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Y-box-binding protein 1 {ECO:0000303|Ref.1}; Short=YB-1 {ECO:0000303|Ref.1};AltName: Full=CCAAT-binding transcription factor I subunit A; Short=CBF-A;AltName: Full=DNA-binding protein B {ECO:0000303|Ref.1}; Short=DBPB

Provider

SWISS-PROT

Sequence

Polypeptide 322 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ybx1	Y box protein 1	122	121	4	25

Sequence references in MGI

J:12573 Tafuri SR, et al., A mouse Y box protein, MSY1, is associated with paternal mRNA in spermatocytes. J Biol Chem. 1993 Jun 5;268(16):12213-20
J:40005 Gai XX, et al., Unusual DNA binding characteristics of an in vitro translation product of the CCAAT binding protein mYB-1. Nucleic Acids Res. 1992 Feb 11;20(3):601-6
J:55001 Kelm RJ Jr, et al., Molecular interactions between single-stranded DNA-binding proteins associated with an essential MCAT element in the mouse smooth muscle alpha-actin promoter. J Biol Chem. 1999 May 14;274(20):14238-45
J:99099 Lu ZH, et al., YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescence. Mol Cell Biol. 2005 Jun;25(11):4625-37
J:151443 Yang XC, et al., Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA. Mol Cell Biol. 2009 Aug;29(15):4045-56
J:231209 Ceman S, et al., Identification of mouse YB1/p50 as a component of the FMRP-associated mRNP particle. Biochem Biophys Res Commun. 2000 Dec 29;279(3):904-8
J:244072 Li S, et al., Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7111-E7120
J:261926 Kwon E, et al., The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018 Apr 30;9(1):1734
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:338157 Kato M, et al., Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-beta-induced collagen expression in kidney cells. J Biol Chem. 2010 Oct 29;285(44):34004-15
J:343118 Rumora AE, et al., Electrostatic and Hydrophobic Interactions Mediate Single-Stranded DNA Recognition and Acta2 Repression by Purine-Rich Element-Binding Protein B. Biochemistry. 2016 May 17;55(19):2794-805