Sequence Detail

ID/Version

P62737 P03996 P04108 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Actin, aortic smooth muscle; EC=3.6.4.- {ECO:0000250|UniProtKB:P68137};AltName: Full=Alpha-actin-2;Contains: RecName: Full=Actin, aortic smooth muscle, intermediate form;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 377 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acta2	actin alpha 2, smooth muscle, aorta	32	410	3	14

Sequence references in MGI

J:9473 Min BH, et al., Nucleotide sequence of a mouse vascular smooth muscle alpha-actin cDNA. Nucleic Acids Res. 1988 Nov 11;16(21):10374
J:10720 Min BH, et al., The 5'-flanking region of the mouse vascular smooth muscle alpha-actin gene contains evolutionarily conserved sequence motifs within a functional promoter. J Biol Chem. 1990 Sep 25;265(27):16667-75
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:201326 Lee BC, et al., MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell. 2013 Aug 8;51(3):397-404
J:262023 Morooka N, et al., Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288
J:331923 Haahr P, et al., Actin maturation requires the ACTMAP/C19orf54 protease. Science. 2022 Sep 30;377(6614):1533-1537