Sequence Detail

ID/Version

P62331 P26438 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=ADP-ribosylation factor 6; EC=3.6.5.2 {ECO:0000250|UniProtKB:P62330};

Provider

SWISS-PROT

Sequence

Polypeptide 175 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arf6	ARF GTPase 6	156	121	4	13

Sequence references in MGI

J:42235 Hosaka M, et al., Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6). J Biochem. 1996 Oct;120(4):813-9
J:156525 Ikenouchi J, et al., FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):748-53
J:168205 Miyazaki H, et al., The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation. FEBS Lett. 2005 Dec 19;579(30):6834-8
J:184675 Makyio H, et al., Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis. EMBO J. 2012;31(11):2590-603
J:188708 Tamaki H, et al., Pilt is a coiled-coil domain-containing protein that localizes at the trans-Golgi complex and regulates its structure. FEBS Lett. 2012 Sep 21;586(19):3064-70
J:201931 Kobayashi H, et al., Rab35 establishes the EHD1-association site by coordinating two distinct effectors during neurite outgrowth. J Cell Sci. 2013 Jun 1;126(Pt 11):2424-35
J:238205 Sivadasan R, et al., C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nat Neurosci. 2016 Dec;19(12):1610-1618
J:257317 Mohanan V, et al., C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions. Science. 2018 Mar 9;359(6380):1161-1166
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89