Sequence Detail

ID/Version

P61372 Q812D8 P20663 P47894 (UniProt | EBI)

Last sequence update: 2004-05-24
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Insulin gene enhancer protein ISL-1; Short=Islet-1;

Provider

SWISS-PROT

Sequence

Polypeptide 349 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Isl1	ISL1 transcription factor, LIM/homeodomain	124	464	4	23

Sequence references in MGI

J:95093 Cai CL, et al., Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell. 2003 Dec;5(6):877-89
J:200395 Bhati M, et al., Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. EMBO J. 2008 Jul 23;27(14):2018-29
J:212665 Huang ZP, et al., CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16;110(6):818-30
J:220735 Wu F, et al., Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):E1559-68
J:239195 Li R, et al., Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells. PLoS One. 2014;9(3):e92105
J:239224 Ando K, et al., Isolation and characterization of an alternatively spliced variant of transcription factor Islet-1. J Mol Endocrinol. 2003 Dec;31(3):419-25
J:328860 Lee S, et al., A regulatory network to segregate the identity of neuronal subtypes. Dev Cell. 2008 Jun;14(6):877-89