Sequence Detail

ID/Version

P60879 A2AIC2 A2AIC3 P70557 Q9BR45 P13795 P36974 Q8IXK3 P70558 Q96FM2 (UniProt | EBI)

Last sequence update: 2004-04-13
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Synaptosomal-associated protein 25; Short=SNAP-25;AltName: Full=Super protein; Short=SUP;AltName: Full=Synaptosomal-associated 25 kDa protein;

Provider

SWISS-PROT

Sequence

Polypeptide 206 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Snap25	synaptosomal-associated protein 25	115	114	4	18

Sequence references in MGI

J:27204 Oyler GA, et al., The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations. J Cell Biol. 1989 Dec;109(6 Pt 1):3039-52
J:52524 Ilardi JM, et al., Snapin: a SNARE-associated protein implicated in synaptic transmission [see comments]. Nat Neurosci. 1999 Feb;2(2):119-24
J:70827 Ehringer MA, et al., High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mamm Genome. 2001 Aug;12(8):657-63
J:95183 Lazzell DR, et al., SV2B regulates synaptotagmin 1 by direct interaction. J Biol Chem. 2004 Dec 10;279(50):52124-31
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112723 Pooley RD, et al., CytLEK1 is a regulator of plasma membrane recycling through its interaction with SNAP-25. Mol Biol Cell. 2006 Jul;17(7):3176-86
J:116097 Roux I, et al., Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse. Cell. 2006 Oct 20;127(2):277-89
J:164218 Burre J, et al., Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7
J:177031 Hu XQ, et al., Acrosome formation-associated factor is involved in fertilization. Fertil Steril. 2010 Mar 15;93(5):1482-92
J:188897 Ghiani CA, et al., The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth. Mol Psychiatry. 2010 Feb;15(2):115, 204-15
J:221517 Lemonidis K, et al., The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity. Mol Biol Cell. 2014 Dec 1;25(24):3870-83
J:233660 Lemonidis K, et al., Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-Acyltransferases. J Biol Chem. 2015 Sep 4;290(36):21939-50
J:235086 Valente P, et al., PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery. Cell Rep. 2016 Apr 5;15(1):117-31
J:249825 Park S, et al., UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans. J Neurosci. 2017 Sep 6;37(36):8797-8815
J:255335 Tan GH, et al., PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum. Cell Res. 2018 Jan;28(1):90-110
J:266473 Ito H, et al., Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin. J Neurochem. 2009 Feb;108(4):867-80
J:279806 Zulliger R, et al., SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS One. 2015;10(9):e0138508
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89