Sequence Detail

ID/Version

P60202 P06905 P04400 Q9WUS9 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Myelin proteolipid protein; Short=PLP;AltName: Full=Lipophilin;

Provider

SWISS-PROT

Sequence

Polypeptide 277 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plp1	proteolipid protein (myelin) 1	32	164	4	27

Sequence references in MGI

J:2126 Schneider A, et al., Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene. Nature. 1992 Aug 27;358(6389):758-61
J:8514 Nave KA, et al., Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing. Proc Natl Acad Sci U S A. 1986 Dec;83(23):9264-8
J:9096 Ikenaka K, et al., Myelin proteolipid protein gene structure and its regulation of expression in normal and jimpy mutant mice. J Mol Biol. 1988 Feb 20;199(4):587-96
J:20245 Hudson LD, et al., Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse. Proc Natl Acad Sci U S A. 1987 Mar;84(5):1454-8
J:26979 Macklin WB, et al., Structure and expression of the mouse myelin proteolipid protein gene. J Neurosci Res. 1987;18(3):383-94
J:28225 Sorg BA, et al., Developmental expression of the myelin proteolipid protein and basic protein mRNAs in normal and dysmyelinating mutant mice. J Neurochem. 1987 Oct;49(4):1146-54
J:42979 Macklin WB, et al., An AG----GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon. FEBS Lett. 1987 Nov 2;223(2):417-21
J:42980 Gencic S, et al., Conservative amino acid substitution in the myelin proteolipid protein of jimpymsd mice. J Neurosci. 1990 Jan;10(1):117-24
J:145263 Werner HB, et al., Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. J Neurosci. 2007 Jul 18;27(29):7717-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89