Sequence Detail

ID/Version

P58467 G3X9W6 (UniProt | EBI)

Last sequence update: 2019-07-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=SET domain-containing protein 4 {ECO:0000305}; EC=2.1.1.- {ECO:0000250|UniProtKB:Q9NVD3}; EC=2.1.1.364 {ECO:0000269|PubMed:31376731};

Provider

SWISS-PROT

Sequence

Polypeptide 439 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Setd4	SET domain containing 4	35	101	3	34

Sequence references in MGI

J:76842 Reymond A, et al., From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Genomics. 2001 Nov;78(1-2):46-54
J:297725 Feng X, et al., Loss of Setd4 delays radiation-induced thymic lymphoma in mice. DNA Repair (Amst). 2020 Feb;86:102754
J:304151 Zhong Y, et al., The novel methyltransferase SETD4 regulates TLR agonist-induced expression of cytokines through methylation of lysine 4 at histone 3 in macrophages. Mol Immunol. 2019 Oct;114:179-188
J:304708 Liao X, et al., SETD4 in the Proliferation, Migration, Angiogenesis, Myogenic Differentiation and Genomic Methylation of Bone Marrow Mesenchymal Stem Cells. Stem Cell Rev Rep. 2021 Jan 27;
J:319811 Feng X, et al., Deletion of Mouse Setd4 Promotes the Recovery of Hematopoietic Failure. Int J Radiat Oncol Biol Phys. 2020 Jul 15;107(4):779-792