Sequence Detail

ID/Version

P58462 Q6P221 Q8CCD9 Q8C5V2 (UniProt | EBI)

Last sequence update: 2001-12-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Forkhead box protein P1;AltName: Full=Forkhead-related transcription factor 1;

Provider

SWISS-PROT

Sequence

Polypeptide 705 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Foxp1	forkhead box P1	110	159	4	44

Sequence references in MGI

J:70542 Shu W, et al., Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem. 2001 Jul 20;276(29):27488-97
J:82200 Lu MM, et al., Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues. Mech Dev. 2002 Dec;119 Suppl 1:S197-202
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:102102 Li S, et al., Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions. Mol Cell Biol. 2004 Jan;24(2):809-22
J:112644 Hu H, et al., Foxp1 is an essential transcriptional regulator of B cell development. Nat Immunol. 2006 Aug;7(8):819-26
J:139297 Dasen JS, et al., Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell. 2008 Jul 25;134(2):304-16
J:141971 Rousso DL, et al., Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons. Neuron. 2008 Jul 31;59(2):226-40
J:160253 Konstantoulas CJ, et al., FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3. J Neurochem. 2010 May;113(4):836-47
J:163662 Zhang Y, et al., Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes Dev. 2010 Aug 15;24(16):1746-57
J:185603 Li S, et al., Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
J:204447 Leishman E, et al., Foxp1 maintains hair follicle stem cell quiescence through regulation of Fgf18. Development. 2013 Sep;140(18):3809-18
J:215934 Wang H, et al., The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells. Nat Immunol. 2014 Jul;15(7):667-75
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89