Sequence Detail

ID/Version

P58390 Q8CCH4 Q3UF29 Q540U9 E9QNY5 (UniProt | EBI)

Last sequence update: 2013-10-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Small conductance calcium-activated potassium channel protein 2 {ECO:0000305}; Short=SK2; Short=SKCa 2; Short=SKCa2;AltName: Full=KCa2.2;

Provider

SWISS-PROT

Sequence

Polypeptide 839 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	54	100	3	16

Sequence references in MGI

J:72099 Ro S, et al., Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2001 Oct;281(4):G964-73
J:86780 Xu Y, et al., Molecular identification and functional roles of a Ca(2+)-activated K+ channel in human and mouse hearts. J Biol Chem. 2003 Dec 5;278(49):49085-94
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104752 Tuteja D, et al., Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes. Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2714-23
J:178200 Tuteja D, et al., Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels. Circ Res. 2010 Oct 1;107(7):851-9
J:231015 Kim G, et al., Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function. Elife. 2016;5:e12637
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:354158 Nie L, et al., Cloning and expression of a small-conductance Ca(2+)-activated K+ channel from the mouse cochlea: coexpression with alpha9/alpha10 acetylcholine receptors. J Neurophysiol. 2004 Apr;91(4):1536-44