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Sequence Detail
ID/Version
P58355 (UniProt | EBI) Last sequence update: 2001-11-16
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Membrane-associated transporter protein;AltName: Full=Melanoma antigen AIM1; Short=Protein AIM-1;AltName: Full=Protein underwhite;AltName: Full=Solute carrier family 45 member 2;
Provider SWISS-PROT
Sequence
Polypeptide 530 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Slc45a2 solute carrier family 45, member 2 22 100 3 25
Sequence references in MGI J:72440 Newton JM, et al., Mutations in the Human Orthologue of the Mouse underwhite Gene (uw) Underlie a New Form of Oculocutaneous Albinism, OCA4. Am J Hum Genet. 2001 Nov;69(5):981-8
J:73518 Fukamachi S, et al., Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka. Nat Genet. 2001 Aug;28(4):381-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:217827 Bartolke R, et al., Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae. Biochem J. 2014 Dec 1;464(2):193-201
J:328663 Liu Y, et al., Ablation of Proton/Glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis. J Invest Dermatol. 2022 Apr 23;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory