Sequence Detail

ID/Version

P58283 Q68FN0 Q3U493 Q6PWY5 Q6P1H8 Q8C1U3 Q3UGM3 Q3UE56 Q8BN27 (UniProt | EBI)

Last sequence update: 2005-01-04
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase RNF216; EC=2.3.2.27;AltName: Full=RING finger protein 216;AltName: Full=RING-type E3 ubiquitin transferase RNF216 {ECO:0000305};AltName: Full=Triad domain-containing protein 3;AltName: Full=UbcM4-interacti

Provider

SWISS-PROT

Sequence

Polypeptide 853 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rnf216	ring finger protein 216	41	96	3	32

Sequence references in MGI

J:56275 Martinez-Noel G, et al., A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4. FEBS Lett. 1999 Jul 9;454(3):257-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:274674 Melnick AF, et al., RNF216 is essential for spermatogenesis and male fertility. Biol Reprod. 2019 May 1;100(5):1132-1134
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:307636 Li D, et al., RNF216 regulates meiosis and PKA stability in the testes. FASEB J. 2021 Apr;35(4):e21460
J:343176 Yang H, et al., RNF216 affects the stability of STAU2 in the hypothalamus. Dev Growth Differ. 2023 Sep;65(7):408-417