Sequence Detail

ID/Version

P58022 Q8C4K0 Q8BS86 Q8BRE6 Q9JJ39 (UniProt | EBI)

Last sequence update: 2005-11-22
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Lysyl oxidase homolog 2; EC=1.4.3.13 {ECO:0000250|UniProtKB:Q9Y4K0};AltName: Full=Lysyl oxidase-like protein 2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 776 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Loxl2	lysyl oxidase-like 2	89	99	4	15

Sequence references in MGI

J:63550 Jourdan-Le Saux C, et al., The mouse lysyl oxidase-like 2 gene (mLOXL2) maps to chromosome 14 and is highly expressed in skin, lung and thymus. Matrix Biol. 2000 May;19(2):179-83
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:184108 Bignon M, et al., Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane. Blood. 2011 Oct 6;118(14):3979-89
J:184120 Iftikhar M, et al., Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation. J Biol Chem. 2011 Jan 14;286(2):909-18
J:251996 Iturbide A, et al., LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation. Mol Cell. 2015 Jun 4;58(5):755-66