Sequence Detail

ID/Version

P56695 Q9Z276 (UniProt | EBI)

Last sequence update: 1999-07-15
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Wolframin;

Provider

SWISS-PROT

Sequence

Polypeptide 890 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wfs1	wolframin ER transmembrane glycoprotein	76	100	4	25

Sequence references in MGI

J:50118 Inoue H, et al., A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome). Nat Genet. 1998 Oct;20(2):143-8
J:50640 Strom TM, et al., Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein. Hum Mol Genet. 1998 Dec;7(13):2021-8
J:93509 Yamaguchi S, et al., Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein. Biochem Biophys Res Commun. 2004 Dec 3;325(1):250-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89