Sequence Detail

ID/Version

P56564 Q99P53 (UniProt | EBI)

Last sequence update: 2002-03-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Excitatory amino acid transporter 1;AltName: Full=Glial high affinity glutamate transporter;AltName: Full=High-affinity neuronal glutamate transporter; Short=GluT-1 {ECO:0000303|PubMed:7903437};AltName: Full=Sodium-dependent glutamat

Provider

SWISS-PROT

Sequence

Polypeptide 543 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	96	145	4	55

Sequence references in MGI

J:16962 Tanaka K, Cloning and expression of a glutamate transporter from mouse brain. Neurosci Lett. 1993 Sep 3;159(1-2):183-6
J:93201 Stoffel W, et al., Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice. Brain Res Mol Brain Res. 2004 Sep 28;128(2):170-81
J:104910 Sarthy VP, et al., Glutamate transport by retinal Muller cells in glutamate/aspartate transporter-knockout mice. Glia. 2005 Jan 15;49(2):184-96
J:111781 Matsugami TR, et al., From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12161-6
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:241032 Krycer JR, et al., The amino acid transporter, SLC1A3, is plasma membrane-localised in adipocytes and its activity is insensitive to insulin. FEBS Lett. 2017 Jan;591(2):322-330
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89