Sequence Detail

ID/Version

P55095 Q3UFE9 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Pro-glucagon;Contains: RecName: Full=Glicentin;Contains: RecName: Full=Glicentin-related polypeptide; Short=GRPP;Contains: RecName: Full=Oxyntomodulin; Short=OXM; Short=OXY;Contains: RecName: Full=Glucagon;C

Provider

SWISS-PROT

Sequence

Polypeptide 180 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gcg	glucagon	37	231	4	26

Sequence references in MGI

J:34511 Rothenberg ME, et al., Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro. J Biol Chem. 1995 Apr 28;270(17):10136-46
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:120493 Furuta M, et al., Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice. J Biol Chem. 2001 Jul 20;276(29):27197-202
J:179825 Ellingsgaard H, et al., Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med. 2011;17(11):1481-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89