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Sequence Detail
P54987 Q3TAA1 Q3U8E8 Q8CBA6 (UniProt | EBI) Last sequence update: 2006-12-12
Last annotation update: 2020-06-17
from provider
RecName: Full=Cis-aconitate decarboxylase; Short=CAD; EC= {ECO:0000269|PubMed:23610393};AltName: Full=Aconitate decarboxylase;AltName: Full=Aconitate decarboxylase 1 {ECO:0000312|MGI:MGI:103206};AltName: Full=Cis-aconitic acid decar
Polypeptide 488 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Acod1 aconitate decarboxylase 1 37 70 9 4
Sequence references in MGI J:25077 Lee CG, et al., Cloning and analysis of gene regulation of a novel LPS-inducible cDNA. Immunogenetics. 1995;41(5):263-70
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196639 Cheon YP, et al., Immune-responsive gene 1 is a novel target of progesterone receptor and plays a critical role during implantation in the mouse. Endocrinology. 2003 Dec;144(12):5623-30
J:196718 Degrandi D, et al., The proinflammatory cytokine-induced IRG1 protein associates with mitochondria. J Interferon Cytokine Res. 2009 Jan;29(1):55-67
J:196954 Michelucci A, et al., Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7820-5
J:196955 Li Y, et al., Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species. J Biol Chem. 2013 Jun 7;288(23):16225-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory