Sequence Detail

ID/Version

P54099 Q9JI28 (UniProt | EBI)

Last sequence update: 2015-03-04
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=DNA polymerase subunit gamma-1; EC=2.7.7.7 {ECO:0000250|UniProtKB:P54098, ECO:0000269|PubMed:26095671};AltName: Full=3'-5' exodeoxyribonuclease; EC=3.1.11.- {ECO:0000250|UniProtKB:P54098};AltName: Full=5'-deoxyribose-phosphat

Provider

SWISS-PROT

Sequence

Polypeptide 1218 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Polg	polymerase (DNA directed), gamma	68	99	3	25

Sequence references in MGI

J:65559 Mott JL, et al., Genomic structure of murine mitochondrial DNA polymerase-gamma. DNA Cell Biol. 2000 Oct;19(10):601-5
J:91077 Trifunovic A, et al., Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature. 2004 May 27;429(6990):417-23
J:343123 Macao B, et al., The exonuclease activity of DNA polymerase gamma is required for ligation during mitochondrial DNA replication. Nat Commun. 2015 Jun 22;6:7303