Sequence Detail

ID/Version

P53762 Q60661 Q921F3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Aryl hydrocarbon receptor nuclear translocator; Short=ARNT protein;AltName: Full=Dioxin receptor, nuclear translocator;AltName: Full=Hypoxia-inducible factor 1-beta; Short=HIF-1-beta; Short=HIF1-beta;

Provider

SWISS-PROT

Sequence

Polypeptide 791 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arnt	aryl hydrocarbon receptor nuclear translocator	107	123	3	38

Sequence references in MGI

J:21381 Li H, et al., Transcriptional activation function of the mouse Ah receptor nuclear translocator. J Biol Chem. 1994 Nov 11;269(45):28098-105
J:25674 Reisz-Porszasz S, et al., Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT). Mol Cell Biol. 1994 Sep;14(9):6075-86
J:52189 Mimura J, et al., Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. Genes Dev. 1999 Jan 1;13(1):20-5
J:65378 Sadek CM, et al., Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development. Mech Dev. 2000 Oct;97(1-2):13-26
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:206107 Wu D, et al., Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain. Mol Cell Biol. 2013 Nov;33(21):4346-56
J:238807 Wu D, et al., NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife. 2016 Oct 26;5:e18790
J:247431 Wu D, et al., Structural integration in hypoxia-inducible factors. Nature. 2015 Aug 20;524(7565):303-8
J:261828 Schulte KW, et al., Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation. Structure. 2017 Jul 5;25(7):1025-1033.e3
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89