Sequence Detail

ID/Version

P53351 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase PLK2; EC=2.7.11.21;AltName: Full=Polo-like kinase 2; Short=PLK-2;AltName: Full=Serine/threonine-protein kinase SNK;AltName: Full=Serum-inducible kinase;

Provider

SWISS-PROT

Sequence

Polypeptide 682 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plk2	polo like kinase 2	84	100	4	6

Sequence references in MGI

J:43404 Simmons DL, et al., Identification of an early-growth-response gene encoding a novel putative protein kinase. Mol Cell Biol. 1992 Sep;12(9):4164-9
J:85756 Ma S, et al., Role of Plk2 (Snk) in mouse development and cell proliferation. Mol Cell Biol. 2003 Oct;23(19):6936-43
J:147239 Inglis KJ, et al., Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system. J Biol Chem. 2009 Jan 30;284(5):2598-602
J:174739 Lee KJ, et al., Requirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memory. Neuron. 2011 Mar 10;69(5):957-73
J:180484 Burns TF, et al., Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells. Mol Cell Biol. 2003 Aug;23(16):5556-71