Sequence Detail

ID/Version

P52850 Q3UDF4 Q549P5 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; EC=2.8.2.8;AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 2; Short=NDST-2;AltName: Full=Mndns;AltName: Full=N-heparan sulfate sulfotransferase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 883 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ndst2	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2	33	106	4	7

Sequence references in MGI

J:17539 Eriksson I, et al., cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin. J Biol Chem. 1994 Apr 8;269(14):10438-43
J:17668 Orellana A, et al., Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line. J Biol Chem. 1994 Jan 21;269(3):2270-6
J:57120 Humphries DE, et al., Heparin is essential for the storage of specific granule proteases in mast cells [see comments]. Nature. 1999 Aug 19;400(6746):769-72
J:57121 Forsberg E, et al., Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme [see comments]. Nature. 1999 Aug 19;400(6746):773-6
J:67535 Aikawa J, et al., Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4. J Biol Chem. 2001 Feb 23;276(8):5876-82
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563