Sequence Detail

ID/Version

P52792 P52791 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Hexokinase-4 {ECO:0000305}; Short=HK4 {ECO:0000305}; EC=2.7.1.1 {ECO:0000269|PubMed:8530440};AltName: Full=Glucokinase {ECO:0000303|PubMed:8575768, ECO:0000303|PubMed:8575769};AltName: Full=Hexokinase type IV {ECO:0000250|Uni

Provider

SWISS-PROT

Sequence

Polypeptide 465 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gck	glucokinase	103	111	3	43

Sequence references in MGI

J:28756 Bali D, et al., Animal model for maturity-onset diabetes of the young generated by disruption of the mouse glucokinase gene. J Biol Chem. 1995 Sep 15;270(37):21464-7
J:29367 Postic C, et al., Cloning and characterization of the mouse glucokinase gene locus and identification of distal liver-specific DNase I hypersensitive sites. Genomics. 1995 Oct 10;29(3):740-50
J:29368 Ishimura-Oka K, et al., Partial structure of the mouse glucokinase gene. Genomics. 1995 Oct 10;29(3):751-4
J:30334 Terauchi Y, et al., Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J Biol Chem. 1995 Dec 22;270(51):30253-6
J:51826 Postic C, et al., Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. J Biol Chem. 1999 Jan 1;274(1):305-15
J:61183 Grimsby J, et al., Characterization of glucokinase regulatory protein-deficient mice. J Biol Chem. 2000 Mar 17;275(11):7826-31
J:75735 Hughes SD, et al., Expression of normal and novel glucokinase mRNAs in anterior pituitary and islet cells. J Biol Chem. 1991 Mar 5;266(7):4521-30
J:207233 Hofmeister-Brix A, et al., Identification of the ubiquitin-like domain of midnolin as a new glucokinase interaction partner. J Biol Chem. 2013 Dec 13;288(50):35824-39
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89