Sequence Detail

ID/Version

P52734 Q921L2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=FYVE, RhoGEF and PH domain-containing protein 1;AltName: Full=Faciogenital dysplasia 1 protein homolog;AltName: Full=Rho/Rac guanine nucleotide exchange factor FGD1; Short=Rho/Rac GEF;AltName: Full=Zinc finger FYVE domain-containing

Provider

SWISS-PROT

Sequence

Polypeptide 960 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fgd1	FYVE, RhoGEF and PH domain containing 1	25	99	3	51

Sequence references in MGI

J:26633 Pasteris NG, et al., Cloning and regional localization of the mouse faciogenital dysplasia (Fgd1) gene. Mamm Genome. 1995 Sep;6(9):658-61
J:85107 Hou P, et al., Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape. Hum Mol Genet. 2003 Aug 15;12(16):1981-93
J:118143 Kostenko EV, et al., Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs. Mol Cell Biol. 2006 Dec;26(23):8964-75
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89