Sequence Detail

ID/Version

P52194 Q80YU3 Q9D2K5 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Calmegin;AltName: Full=A2/6;AltName: Full=Calnexin-T;AltName: Full=MEG 1 antigen;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 611 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Clgn	calmegin	25	101	3	18

Sequence references in MGI

J:17254 Watanabe D, et al., Molecular cloning of a novel Ca(2+)-binding protein (calmegin) specifically expressed during male meiotic germ cell development. J Biol Chem. 1994 Mar 11;269(10):7744-9
J:18191 Ohsako S, et al., Molecular cloning and sequencing of calnexin-t. An abundant male germ cell-specific calcium-binding protein of the endoplasmic reticulum. J Biol Chem. 1994 May 13;269(19):14140-8
J:40831 Ikawa M, et al., The putative chaperone calmegin is required for sperm fertility. Nature. 1997 Jun 5;387(6633):607-11
J:45097 Tanaka H, et al., Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone. Gene. 1997 Dec 19;204(1-2):159-63
J:59475 Yoshinaga K, et al., Molecular chaperone calmegin localization to the endoplasmic reticulum of meiotic and post-meiotic germ cells in the mouse testis. Arch Histol Cytol. 1999 Aug;62(3):283-93
J:73341 Ikawa M, et al., Calmegin Is Required for Fertilin alpha/beta Heterodimerization and Sperm Fertility. Dev Biol. 2001 Dec 1;240(1):254-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114470 Yamaguchi R, et al., Aberrant Distribution of ADAM3 in Sperm from Both Angiotensin-Converting Enzyme (Ace)- and Calmegin (Clgn)-Deficient Mice. Biol Reprod. 2006 Nov;75(5):760-6
J:160202 Nakanishi T, et al., Selective passage through the uterotubal junction of sperm from a mixed population produced by chimeras of calmegin-knockout and wild-type male mice. Biol Reprod. 2004 Sep;71(3):959-65
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89