Sequence Detail

ID/Version

P51829 Q3U3P2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Adenylate cyclase type 7 {ECO:0000305}; EC=4.6.1.1 {ECO:0000305|PubMed:23229509};AltName: Full=ATP pyrophosphate-lyase 7;AltName: Full=Adenylate cyclase type VII;AltName: Full=Adenylyl cyclase 7;

Provider

SWISS-PROT

Sequence

Polypeptide 1099 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adcy7	adenylate cyclase 7	26	106	3	6

Sequence references in MGI

J:21500 Watson PA, et al., Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells. J Biol Chem. 1994 Nov 18;269(46):28893-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:140266 Jiang LI, et al., Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII. J Biol Chem. 2008 Aug 22;283(34):23429-39
J:161446 Duan B, et al., Distinct roles of adenylyl cyclase VII in regulating the immune responses in mice. J Immunol. 2010 Jul 1;185(1):335-44
J:191067 Jiang LI, et al., Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation. Mol Immunol. 2013 May;54(1):14-22
J:261837 Jiang LI, et al., Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway. Mol Pharmacol. 2013 Mar;83(3):587-93
J:262337 Mann L, et al., Lithium preferentially inhibits adenylyl cyclase V and VII isoforms. Int J Neuropsychopharmacol. 2008 Jun;11(4):533-9