Sequence Detail

ID/Version

P51576 Q5SRU4 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=P2X purinoceptor 1; Short=P2X1;AltName: Full=ATP receptor;AltName: Full=Purinergic receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 399 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	100	102	3	13

Sequence references in MGI

J:33459 Valera S, et al., Characterization and chromosomal localization of a human P2X receptor from the urinary bladder. Receptors Channels. 1995;3(4):283-9
J:59336 Mulryan K, et al., Reduced vas deferens contraction and male infertility in mice lacking P2X1 receptors [see comments]. Nature. 2000 Jan 6;403(6765):86-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:151471 Lecut C, et al., P2X1 Ion channels promote neutrophil chemotaxis through Rho kinase activation. J Immunol. 2009 Aug 15;183(4):2801-9
J:218708 Darbousset R, et al., P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice. Blood. 2014 Oct 16;124(16):2575-85