Sequence Detail

ID/Version

P51163 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Uroporphyrinogen-III synthase; Short=UROIIIS; Short=UROS; EC=4.2.1.75 {ECO:0000305|PubMed:7607680};AltName: Full=Hydroxymethylbilane hydrolyase [cyclizing];AltName: Full=Uroporphyrinogen-III cosynthase;

Provider

SWISS-PROT

Sequence

Polypeptide 265 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Uros	uroporphyrinogen III synthase	44	99	3	19

Sequence references in MGI

J:21509 Bensidhoum M, et al., The cDNA sequence of mouse uroporphyrinogen III synthase and assignment to mouse chromosome 7. Mamm Genome. 1994 Nov;5(11):728-30
J:25240 Xu W, et al., Uroporphyrinogen-III synthase: molecular cloning, nucleotide sequence, expression of a mouse full-length cDNA, and its localization on mouse chromosome 7. Genomics. 1995 Apr 10;26(3):556-62
J:202914 Blouin JM, et al., Therapeutic potential of proteasome inhibitors in congenital erythropoietic porphyria. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18238-43
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89