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Sequence Detail
P50462 (UniProt | EBI) Last sequence update: 1996-10-01
Last annotation update: 2018-03-28
from provider
RecName: Full=Cysteine and glycine-rich protein 3;AltName: Full=Cysteine-rich protein 3; Short=CRP3;AltName: Full=LIM domain protein, cardiac;AltName: Full=Muscle LIM protein;
Polypeptide 194 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Csrp3 cysteine and glycine-rich protein 3 45 9 9 5
Sequence references in MGI J:33993 Harrod GV, et al., Murine MLP: cloning and expression in the embryonic head. J Craniofac Genet Dev Biol. 1996 Apr-Jun;16(2):65-73
J:38213 Arber S, et al., MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell. 1997 Feb 7;88(3):393-403
J:96468 Heineke J, et al., Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1655-60
J:161906 Jeong D, et al., PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling. Circ Res. 2008 Mar 28;102(6):711-9
J:170878 Knoll R, et al., A common MLP (muscle LIM protein) variant is associated with cardiomyopathy. Circ Res. 2010 Mar 5;106(4):695-704
J:240063 Lange S, et al., MLP and CARP are linked to chronic PKCalpha signalling in dilated cardiomyopathy. Nat Commun. 2016 Jun 29;7:12120

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last database update
MGI 6.12
The Jackson Laboratory