Sequence Detail

ID/Version

P50462 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cysteine and glycine-rich protein 3;AltName: Full=Cysteine-rich protein 3; Short=CRP3;AltName: Full=LIM domain protein, cardiac;AltName: Full=Muscle LIM protein;

Provider

SWISS-PROT

Sequence

Polypeptide 194 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Csrp3	cysteine and glycine-rich protein 3	77	113	3	9

Sequence references in MGI

J:33993 Harrod GV, et al., Murine MLP: cloning and expression in the embryonic head. J Craniofac Genet Dev Biol. 1996 Apr-Jun;16(2):65-73
J:38213 Arber S, et al., MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell. 1997 Feb 7;88(3):393-403
J:96468 Heineke J, et al., Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1655-60
J:161906 Jeong D, et al., PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling. Circ Res. 2008 Mar 28;102(6):711-9
J:170878 Knoll R, et al., A common MLP (muscle LIM protein) variant is associated with cardiomyopathy. Circ Res. 2010 Mar 5;106(4):695-704
J:240063 Lange S, et al., MLP and CARP are linked to chronic PKCalpha signalling in dilated cardiomyopathy. Nat Commun. 2016 Jun 29;7:12120
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89