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Sequence Detail
P50220 (UniProt | EBI) Last sequence update: 1996-10-01
Last annotation update: 2018-03-28
from provider
RecName: Full=Homeobox protein Nkx-2.1;AltName: Full=Thyroid nuclear factor 1;AltName: Full=Thyroid transcription factor 1; Short=TTF-1;AltName: Full=Thyroid-specific enhancer-binding protein; Short=T/EBP;
Polypeptide 372 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Nkx2-1 NK2 homeobox 1 113 95 8 10
Sequence references in MGI J:24249 Oguchi H, et al., The complete nucleotide sequence of the mouse thyroid-specific enhancer-binding protein (T/EBP) gene: extensive identity of the deduced amino acid sequence with the human protein. Biochim Biophys Acta. 1995 Apr 4;1261(2):304-6
J:211237 Matagne V, et al., Thyroid transcription factor 1, a homeodomain containing transcription factor, contributes to regulating periodic oscillations in GnRH gene expression. J Neuroendocrinol. 2012 Jun;24(6):916-29
J:217271 Varma S, et al., The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem. 2012 Oct 26;287(44):37282-95

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory