Sequence Detail

ID/Version

P50220 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Homeobox protein Nkx-2.1;AltName: Full=Thyroid nuclear factor 1;AltName: Full=Thyroid transcription factor 1; Short=TTF-1;AltName: Full=Thyroid-specific enhancer-binding protein; Short=T/EBP;

Provider

SWISS-PROT

Sequence

Polypeptide 372 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nkx2-1	NK2 homeobox 1	138	268	3	17

Sequence references in MGI

J:24249 Oguchi H, et al., The complete nucleotide sequence of the mouse thyroid-specific enhancer-binding protein (T/EBP) gene: extensive identity of the deduced amino acid sequence with the human protein. Biochim Biophys Acta. 1995 Apr 4;1261(2):304-6
J:211237 Matagne V, et al., Thyroid transcription factor 1, a homeodomain containing transcription factor, contributes to regulating periodic oscillations in GnRH gene expression. J Neuroendocrinol. 2012 Jun;24(6):916-29
J:217271 Varma S, et al., The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation. J Biol Chem. 2012 Oct 26;287(44):37282-95