Sequence Detail

ID/Version

P49446 Q62444 Q61042 Q60986 Q64496 Q62134 Q3U369 (UniProt | EBI)

Last sequence update: 2009-12-15
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Receptor-type tyrosine-protein phosphatase epsilon; Short=Protein-tyrosine phosphatase epsilon; Short=R-PTP-epsilon; EC=3.1.3.48;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 699 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptpre	protein tyrosine phosphatase receptor type E	26	99	4	4

Sequence references in MGI

J:4150 Schepens J, et al., Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain. Mol Biol Rep. 1992 Sep;16(4):241-8
J:22419 Hendriks W, et al., A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain. Biochem J. 1995 Jan 15;305(Pt 2):499-504
J:29004 Yi T, et al., Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification. Blood. 1991 Nov 1;78(9):2222-8
J:29711 Elson A, et al., Protein-tyrosine phosphatase epsilon. An isoform specifically expressed in mouse mammary tumors initiated by v-Ha-ras OR neu. J Biol Chem. 1995 Nov 3;270(44):26116-22
J:42342 Schmidt A, et al., Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):3068-73
J:42343 Elson A, et al., Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon. Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12235-9
J:64794 Gil-Henn H, et al., Generation of novel cytoplasmic forms of protein tyrosine phosphatase epsilon by proteolytic processing and translational control. Oncogene. 2000 Sep 7;19(38):4375-84
J:84553 Toledano-Katchalski H, et al., Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon. Mol Cell Biol. 2003 Aug;23(15):5460-71
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:131128 Aga-Mizrachi S, et al., Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle. Endocrinology. 2008 Feb;149(2):605-14
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:155066 Akimoto M, et al., Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses. Scand J Immunol. 2009 May;69(5):401-11
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89