Sequence Detail

ID/Version

P48453 Q6NZR4 (UniProt | EBI)

Last sequence update: 2004-11-09
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; EC=3.1.3.16 {ECO:0000250|UniProtKB:P16298};AltName: Full=CAM-PRP catalytic subunit;AltName: Full=Calmodulin-dependent calcineurin A subunit beta isoform;

Provider

SWISS-PROT

Sequence

Polypeptide 525 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	78	107	2	26

Sequence references in MGI

J:368 Giri PR, et al., Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Biochem Biophys Res Commun. 1991 Nov 27;181(1):252-8
J:54583 Zhuo M, et al., A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4650-5
J:93625 Gooch JL, et al., Calcineurin A-alpha but not A-beta is required for normal kidney development and function. Am J Pathol. 2004 Nov;165(5):1755-65
J:110822 Parsons SA, et al., Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice. Mol Cell Biol. 2003 Jun;23(12):4331-43
J:169854 Reddy RN, et al., Rescue of Calcineurin Aalpha(-/-) Mice Reveals a Novel Role for the alpha Isoform in the Salivary Gland. Am J Pathol. 2011 Apr;178(4):1605-13
J:282598 Chaya T, et al., Cul3-Klhl18 ubiquitin ligase modulates rod transducin translocation during light-dark adaptation. EMBO J. 2019 Dec 2;38(23):e101409
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:319680 Shinzawa M, et al., Catalytic subunits of the phosphatase calcineurin interact with NF-kappaB-inducing kinase (NIK) and attenuate NIK-dependent gene expression. Sci Rep. 2015 Jun 1;5:10758