Sequence Detail

ID/Version

P48381 Q8VBY6 Q8BLW2 Q8C0R3 (UniProt | EBI)

Last sequence update: 2003-06-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Transcription factor RFX3;AltName: Full=Regulatory factor X 3;

Provider

SWISS-PROT

Sequence

Polypeptide 749 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rfx3	regulatory factor X, 3 (influences HLA class II expression)	30	105	3	41

Sequence references in MGI

J:32459 Reith W, et al., RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol Cell Biol. 1994 Feb;14(2):1230-44
J:89880 Bonnafe E, et al., The transcription factor RFX3 directs nodal cilium development and left-right asymmetry specification. Mol Cell Biol. 2004 May;24(10):4417-27
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112926 Baas D, et al., A deficiency in RFX3 causes hydrocephalus associated with abnormal differentiation of ependymal cells. Eur J Neurosci. 2006 Aug;24(4):1020-30
J:122122 Ait-Lounis A, et al., Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas. Diabetes. 2007 Apr;56(4):950-9
J:153136 El Zein L, et al., RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies. J Cell Sci. 2009 Sep 1;122(Pt 17):3180-9