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Sequence Detail
ID/Version
P48379 Q8BXR3 (UniProt | EBI) Last sequence update: 2009-07-28
Last annotation update: 2019-09-18
Sequence
description
from provider
RecName: Full=DNA-binding protein RFX2;AltName: Full=Regulatory factor X 2;
Provider SWISS-PROT
Sequence
Polypeptide 717 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Rfx2 regulatory factor X, 2 (influences HLA class II expression) 24 10 9 98
Sequence references in MGI J:32459 Reith W, et al., RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol Cell Biol. 1994 Feb;14(2):1230-44
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:182770 Bisgrove BW, et al., RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow. Dev Biol. 2012 Mar 1;363(1):166-78
J:227136 Shawlot W, et al., Rfx2 is required for spermatogenesis in the mouse. Genesis. 2015 Aug 6;
J:228765 Kistler WS, et al., RFX2 Is a Major Transcriptional Regulator of Spermiogenesis. PLoS Genet. 2015 Jul;11(7):e1005368
J:230575 Wu Y, et al., Transcription Factor RFX2 Is a Key Regulator of Mouse Spermiogenesis. Sci Rep. 2016;6:20435

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory