Sequence Detail

ID/Version

P48379 Q8BXR3 (UniProt | EBI)

Last sequence update: 2009-07-28
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA-binding protein RFX2;AltName: Full=Regulatory factor X 2;

Provider

SWISS-PROT

Sequence

Polypeptide 717 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rfx2	regulatory factor X, 2 (influences HLA class II expression)	35	107	3	90

Sequence references in MGI

J:32459 Reith W, et al., RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol Cell Biol. 1994 Feb;14(2):1230-44
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:182770 Bisgrove BW, et al., RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow. Dev Biol. 2012 Mar 1;363(1):166-78
J:227136 Shawlot W, et al., Rfx2 is required for spermatogenesis in the mouse. Genesis. 2015 Aug 6;
J:228765 Kistler WS, et al., RFX2 Is a Major Transcriptional Regulator of Spermiogenesis. PLoS Genet. 2015 Jul;11(7):e1005368
J:230575 Wu Y, et al., Transcription Factor RFX2 Is a Key Regulator of Mouse Spermiogenesis. Sci Rep. 2016;6:20435
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89