Sequence Detail

ID/Version

P48320 O35519 (UniProt | EBI)

Last sequence update: 1996-02-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Glutamate decarboxylase 2; EC=4.1.1.15;AltName: Full=65 kDa glutamic acid decarboxylase; Short=GAD-65;AltName: Full=Glutamate decarboxylase 65 kDa isoform;

Provider

SWISS-PROT

Sequence

Polypeptide 585 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gad2	glutamic acid decarboxylase 2	29	147	3	20

Sequence references in MGI

J:15455 Lee DS, et al., Cloning and sequence analysis of a murine cDNA encoding glutamate decarboxylase (GAD65). Biochim Biophys Acta. 1993 Oct 19;1216(1):157-60
J:16138 Faulkner-Jones BE, et al., Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat. Endocrinology. 1993 Dec;133(6):2962-72
J:37576 Asada H, et al., Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures. Biochem Biophys Res Commun. 1996 Dec 24;229(3):891-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89