Sequence Detail

ID/Version

P47931 A6H6P0 (UniProt | EBI)

Last sequence update: 1996-02-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Follistatin {ECO:0000303|PubMed:7600958}; Short=FS;AltName: Full=Activin-binding protein {ECO:0000303|PubMed:7956942};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 344 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fst	follistatin	40	163	4	19

Sequence references in MGI

J:17693 Albano RM, et al., Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain. Development. 1994 Apr;120(4):803-13
J:23925 Matzuk MM, et al., Multiple defects and perinatal death in mice deficient in follistatin [see comments]. Nature. 1995 Mar 23;374(6520):360-3
J:182827 Lee SJ, et al., Regulation of muscle mass by follistatin and activins. Mol Endocrinol. 2010 Oct;24(10):1998-2008
J:185267 Winbanks CE, et al., Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin. J Cell Biol. 2012 Jun 25;197(7):997-1008
J:306591 Davey JR, et al., Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass. JCI Insight. 2016 Apr 21;1(5):e85477