Sequence Detail

ID/Version

P46737 A3KGA9 Q3UDZ4 A8Y5K0 Q9D025 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Lys-63-specific deubiquitinase BRCC36; EC=3.4.19.- {ECO:0000250|UniProtKB:P46736};AltName: Full=BRCA1-A complex subunit BRCC36;AltName: Full=BRCA1/BRCA2-containing complex subunit 3;AltName: Full=BRCA1/BRCA2-containing complex subuni

Provider

SWISS-PROT

Sequence

Polypeptide 291 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Brcc3	BRCA1/BRCA2-containing complex, subunit 3	76	98	3	15

Sequence references in MGI

J:57583 Fisch P, et al., The chromosomal translocation t(X;14)(q28;q11) in T-cell pro-lymphocytic leukaemia breaks within one gene and activates another. Oncogene. 1993 Dec;8(12):3271-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:251887 Song N, et al., NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation. Mol Cell. 2017 Oct 5;68(1):185-197.e6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:319940 Yan L, et al., PWWP2B Fine-Tunes Adipose Thermogenesis by Stabilizing HDACs in a NuRD Subcomplex. Adv Sci (Weinh). 2021 Aug;8(16):e2102060
J:331359 Py BF, et al., Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol Cell. 2013 Jan 24;49(2):331-8