Sequence Detail

ID/Version

P46684 Q80Y18 Q6PAK5 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Zinc finger protein ZIC 1;AltName: Full=Zinc finger protein of the cerebellum 1;

Provider

SWISS-PROT

Sequence

Polypeptide 447 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zic1	zinc finger protein of the cerebellum 1	56	148	3	8

Sequence references in MGI

J:31270 Aruga J, et al., A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells. J Neurochem. 1994 Nov;63(5):1880-90
J:76132 Aruga J, et al., Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation. Dev Biol. 2002 Apr 15;244(2):329-41
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114033 Koyabu Y, et al., Physical and functional interactions between Zic and Gli proteins. J Biol Chem. 2001 Mar 9;276(10):6889-92
J:152943 Dipietrantonio HJ, et al., Zic1 levels regulate mossy fiber neuron position and axon laterality choice in the ventral brain stem. Neuroscience. 2009 Sep 1;162(3):560-73
J:162345 Kalogeropoulos M, et al., Zic1 transcription factor in bone: neural developmental protein regulates mechanotransduction in osteocytes. FASEB J. 2010 Aug;24(8):2893-903
J:169807 Mizugishi K, et al., Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. J Biol Chem. 2001 Jan 19;276(3):2180-8
J:169910 Mizugishi K, et al., Myogenic repressor I-mfa interferes with the function of Zic family proteins. Biochem Biophys Res Commun. 2004 Jul 16;320(1):233-40