Sequence Detail

ID/Version

P46662 Q8BR03 (UniProt | EBI)

Last sequence update: 2003-06-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Merlin;AltName: Full=Moesin-ezrin-radixin-like protein;AltName: Full=Neurofibromin-2;AltName: Full=Schwannomin;

Provider

SWISS-PROT

Sequence

Polypeptide 596 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nf2	neurofibromin 2	87	114	3	96

Sequence references in MGI

J:17367 Haase VH, et al., The murine NF2 homologue encodes a highly conserved merlin protein with alternative forms. Hum Mol Genet. 1994 Mar;3(3):407-11
J:18475 Claudio JO, et al., The mouse neurofibromatosis type 2 gene maps to chromosome 11. Genomics. 1994 May 15;21(2):437-9
J:19215 Huynh DP, et al., Alternative transcripts in the mouse neurofibromatosis type 2 (NF2) gene are conserved and code for schwannomins with distinct C-terminal domains. Hum Mol Genet. 1994 Jul;3(7):1075-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161172 Wiley LA, et al., The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3611-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89