Sequence Detail

ID/Version

P46062 P70204 (UniProt | EBI)

Last sequence update: 2002-05-02
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Signal-induced proliferation-associated protein 1; Short=Sipa-1;AltName: Full=GTPase-activating protein Spa-1;

Provider

SWISS-PROT

Sequence

Polypeptide 1037 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sipa1	signal-induced proliferation associated gene 1	15	97	3	8

Sequence references in MGI

J:35455 Hattori M, et al., Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression. Mol Cell Biol. 1995 Jan;15(1):552-60
J:37839 Wada Y, et al., Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human. Genomics. 1997 Jan 1;39(1):66-73
J:43709 Kurachi H, et al., Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product. J Biol Chem. 1997 Oct 31;272(44):28081-8
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:245239 Crawford NP, et al., Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis. PLoS Genet. 2007 Nov;3(11):e214
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89