Sequence Detail

ID/Version

P45952 Q64235 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Medium-chain specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000305|PubMed:7829081}; Short=MCAD {ECO:0000303|PubMed:7829081}; EC=1.3.8.7 {ECO:0000269|PubMed:16121256};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 421 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Acadm	acyl-Coenzyme A dehydrogenase, medium chain	75	116	3	47

Sequence references in MGI

J:20148 Tolwani RJ, et al., Molecular cloning and characterization of the mouse medium-chain acyl-CoA dehydrogenase cDNA. Genomics. 1994 Sep 1;23(1):247-9
J:115759 Tolwani RJ, et al., Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice. PLoS Genet. 2005 Aug;1(2):e23
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89