Sequence Detail

ID/Version

P43120 Q544N6 Q9R1X2 Q9CRV1 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Hematopoietically-expressed homeobox protein Hhex; Short=Homeobox protein HEX; Short=mHex;AltName: Full=Homeobox protein PRH;AltName: Full=Proline-rich homeodomain protein {ECO:0000303|PubMed:12554669};

Provider

SWISS-PROT

Sequence

Polypeptide 271 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hhex	hematopoietically expressed homeobox	88	163	3	20

Sequence references in MGI

J:4210 Bedford FK, et al., HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human. Nucleic Acids Res. 1993 Mar 11;21(5):1245-9
J:54779 Myint Z, et al., Genomic organization and promoter analysis of a mouse homeobox gene, Hex. J Biochem. 1999 Apr;125(4):795-802
J:57839 Ghosh B, et al., Genomic structure, cDNA mapping, and chromosomal localization of the mouse homeobox gene, Hex. Mamm Genome. 1999 Oct;10(10):1023-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:133012 Zamparini AL, et al., Hex acts with beta-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal. Development. 2006 Sep;133(18):3709-22
J:133018 Brickman JM, et al., Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function. Development. 2000 Jun;127(11):2303-15
J:161671 Marfil V, et al., Interaction between Hhex and SOX13 modulates Wnt/TCF activity. J Biol Chem. 2010 Feb 19;285(8):5726-37
J:197437 Bhave VS, et al., Regulation of liver growth by glypican 3, CD81, hedgehog, and hhex. Am J Pathol. 2013 Jul;183(1):153-9