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Sequence Detail
ID/Version
P42703 Q5I0Y2 (UniProt | EBI) Last sequence update: 1995-11-01
Last annotation update: 2025-06-18
Sequence
description
from provider
RecName: Full=Leukemia inhibitory factor receptor; Short=LIF receptor; Short=LIF-R;AltName: Full=D-factor/LIF receptor;AltName: CD_antigen=CD118;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 1092 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Lifr LIF receptor alpha 48 147 4 42
Sequence references in MGI J:18353 Tomida M, et al., Three different cDNAs encoding mouse D-factor/LIF receptor. J Biochem. 1994 Mar;115(3):557-62
J:29552 Gearing DP, et al., Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J. 1991 Oct;10(10):2839-48
J:31510 Tomida M, et al., Pregnancy associated increase in mRNA for soluble D-factor/LIF receptor in mouse liver. FEBS Lett. 1993 Nov 15;334(2):193-7
J:123404 Huyton T, et al., An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12737-42
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory