Sequence Detail

ID/Version

P42703 Q5I0Y2 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Leukemia inhibitory factor receptor; Short=LIF receptor; Short=LIF-R;AltName: Full=D-factor/LIF receptor;AltName: CD_antigen=CD118;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1092 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lifr	LIF receptor alpha	48	147	4	42

Sequence references in MGI

J:18353 Tomida M, et al., Three different cDNAs encoding mouse D-factor/LIF receptor. J Biochem. 1994 Mar;115(3):557-62
J:29552 Gearing DP, et al., Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J. 1991 Oct;10(10):2839-48
J:31510 Tomida M, et al., Pregnancy associated increase in mRNA for soluble D-factor/LIF receptor in mouse liver. FEBS Lett. 1993 Nov 15;334(2):193-7
J:123404 Huyton T, et al., An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12737-42
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89